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Many bodybuilding drugs aim to build the levels of testosterone in your body, but testosterone also has some adverse side effectswith prolonged use, such as bone loss, low libido, increased heart rate, and anxiety. Caffeine Caffeine is often used in the supplement industry to improve sleep or increase energy levels, but recent research has revealed it may be detrimental to growth hormone levels. An Australian study discovered caffeine enhances the effect of testosterone on the growth hormone receptors on the pituitary gland, resulting in increased testosterone production throughout the day. Dextro-Alpha-lipoic acid Dextro-Alpha-lipoic acid has been shown to have anti-angiogenic properties. DHA reduces cholesterol levels in arteries and arteries in fish, fish oil, and eggs. DHA has been demonstrated to enhance prostate cell growth. The results of this study, which was published in the journal Endocrinology, suggest DHA has potential benefit for treatment of prostate cancer patients that do not undergo radiation. Some researchers claim DHA may also aid in lowering body fat by encouraging the use of exercise. Eicosapentaenoic acid Eicosapentaenoic acid (EPA) also plays a role in the regulation of estrogen hormones such as estrogen and progesterone, and may reduce estrogen levels in an animal model. EPA may also help stimulate the growth of osteoblasts. Other nutrients In general, the list of nutrients that supplement companies recommend may be over-priced. To help you make sense of all of the nutritional options available to you, our nutrition supplement database contains a complete list of over 600 nutrient-rich natural products. Our complete guide lists the best supplements for muscle growth, maintenance, and recovery, and our complete supplement guide lists the best supplements to prevent or treat illness. References 1. Schoenfeld T, Heaney RP, Hennin D, Schloss M et al. Pharmacokinetics of the combined oral dose of testosterone hydrochloride and caffeine in healthy male volunteers. J Clin Endocrinol Metab 1995;80(2):1593-1597. 2. Tse JL, Krasnow JF, Chen J et al. Effects of nandrolone decanoate, nacrolimus, caffeine, and chlordiazepoxide in healthy male volunteers. J Clin Endocrinol Metab 1996;81(6):3896-3899. Related Article: